Paracrine Bone Morphogenetic Protein Signaling in Iron Homeostasis
نویسندگان
چکیده
منابع مشابه
Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis
Mutations in hemojuvelin (HJV) are the most common cause of the juvenile-onset form of the iron overload disorder hereditary hemochromatosis. The discovery that HJV functions as a co-receptor for the bone morphogenetic protein (BMP) family of signaling molecules helped to identify this signaling pathway as a central regulator of the key iron hormone hepcidin in the control of systemic iron home...
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ژورنال
عنوان ژورنال: Blood
سال: 2019
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2019-121069